There is many way to investigate malware and to “find evil” in an unknown executable. There will be situation where looking at a list of running processes won’t give you information to raise a red flag. You can always go deeper and perform more manual analysis. Even though this might be fun it might also be very time consuming…and we don’t always have the luxury of time neither the resources.
Analysis of mutexes (sometime called mutant) can be a pretty good way to continue your analysis and find more evidence of “evil”.